Tuesday, August 19, 2025

Lets go for the 3 Rs

Plastic,  would create a world brighter and clearer than any previously known […] a world free from moth and rust and full of colour”.   “A world in which man, like a magician makes what he wants for almost every need….” (From a book on Plastics written in 1941)

We woke up to the dangers of plastic waste accumulating around us during the  seventies.  Packaging  and single use plastics  make up the major chunk of plastic waste.  But remember single-use plastics  are also  essential  for healthcare applications such as personal protective equipments, syringes, sterile packaging,  life support equipment, etc. In brief we have gotten so used to the convenience of the disposable plastics that we cannot live without them. Of course   there have been attempts to  contain plastic waste.  Biodegradable alternatives have  proved to be too costly to adopt.  Also  there are legitimate concerns about their performance.   Now attempts are on for popularizing the 3Rs;  Reduce, Reuse, Recycle.  This again  is not a smooth path forward.  It is a pity that   The  Intergovernmental Negotiating Committee on Plastics Pollution  which   met  from  5 to 15 August 2025  in Geneva, Switzerland  failed to arrive at an international legally binding resolution.  Because India, United States,  China and several Arab countries  don't want  any curb on plastics production. 

Courtesy: Wikipedia    

But now an associated  major  concern is looming large.  The discarded plastic items weathered by water, wind, sunlight or heat  or even by  tearing and friction,    disintegrates   yielding   smaller particles which are of micrometer or  nanometer in size. Collectively called MNPs (Micro&Nano Plastics)  these  have become ubiquitous: they can enter our body through the air we breathe,  through the food we eat, and drink.  MNPs have been found in  human saliva, blood, breast milk and  in  the liver, kidneys, spleen, brain and even  bones. There was a time when  specially designed  microbeads were added to formulations such as toothpaste and scrubbing creams to enhance  abrasion, a practice which has since  been discarded. In a recent podcast, Professor Matthew Campen, University of New Mexico  cautions us: Beware of tiny plastic particles, these are invading  our  bodies  including the brain and  organs.    In a study conducted on postmortem liver, kidney and brain samples, MNPs were detected in higher concentration the brain  than in the liver or kidney. The brain samples of  dementia patients registered higher MNP content.  In another  study conducted in Netherlands, 17 out of   22 volunteers had MNPs in their blood samples. 

We are now faced with a key question: Human body has a robust clearing  process. Generally if we inhale or swallow anything  unwanted/undigestible/alien, our  body gets rid of them all, through cough,   through urine or feces.  Then  how do MNPs escape  this clearing process?   To answer   we need   a standardized  approach across laboratories  to quantify and analyze  MNPs in biological tissues/organs.  To begin with   uniform  well defined, reproducible  protocols  for  human tissue collection,  precautions  for minimizing contamination and robust  controls, detection methods  etc should be adopted.   With these guidelines in place   biological processes such as absorption, metabolism, transportation, and accumulation of MNPs  as well as  their ability to  cross biological barriers  should be monitored. This will facilitate comparing  results from across the globe  and allow conclusions to be drawn. Currently comprehensive  epidemiological studies on  MNPs are lacking.

That  leads us to the next more critical  question:  how exactly  are MNPs messing up our health? Unfortunately here again  we don't have clear answers  as of now.  What we have are speculations and possibilities which are alarming.   There is general consensus  that  MNPs could cause serious  biological  complications for us  in the long run.  Perhaps it might take a generation or two for  manifestation.  For the time being the best  policy will be to rely on the 3Rs: Reduce, Reuse, Recycle.

TAIL PIECE:

Courtesy: wikipedia




REFEREMNCES:

1. How microplastics are invading our bodies

2. Bioaccumulation of microplastics in decedent human brains 

3. Microplastics: A Real Global Threat for Environment and Food Safety: A State of the Art Review